What is the difference between total and free Testosterone?
Sex-hormone binding globulin (SHBG) or albumin binds around 98 percent of the testosterone produced by the body. The term for this is "bound testosterone." The remaining 2% is referred to as "free testosterone."
This unattached, unbound or "free" testosterone binds to testosterone receptors in the cells of the body. Free testosterone promotes a cell's functions, like cell reproduction in the bones and muscles, by allowing it to absorb it. In males, free testosterone is also responsible for developing secondary sexual traits. Face hair and a deeper voice are examples of this.
Total testosterone is the sum of all hormones present in the circulation, as the name implies. While some testosterone tests solely measure total testosterone, they may not be as useful as previously believed. For bound testosterone, a 98 percent percentage is considered typical, though aberrations might arise. Testing just for total testosterone levels ignores the potential of high SHBG or albumin bonding. Here's why it's important. Due to the risk of severe bondage, it is conceivable to have normal total testosterone levels but inadequate free testosterone to fulfil vital duties. Too little free testosterone may cause poor muscular growth, irritation, decreased libido desire, and a variety of other disorders that aren't immediately associated with it.
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As a result, although total testosterone levels may seem to be normal, low free testosterone levels may lead to incorrect diagnosis and therapy. A patient, for example, may not need any more testosterone. They may just need less chemicals that convert testosterone to other hormones like oestrogen. This is why testing for free testosterone levels, rather than simply total testosterone, may be crucial.
How to Increase Free State Testosterone Levels
Free testosterone levels may be increased in two ways. Anything that raises total testosterone levels (such as exercise or supplementation) will likewise raise free testosterone levels. The alternative option is to lower SHBG-bound testosterone levels.
While the normal ageing process promotes SHBG bonding, some variables may hasten the process. SHBG bonding is known to be affected by hormone levels such as insulin, growth hormone, oestrogen, and thyroid hormones. SHBG is hypothesised to be reduced by vitamins and botanicals, such as vitamin D and boron.
Erectile Dysfunction and Hormonal Imbalances
Testosterone is plainly important for a man's sexual function. Erectile dysfunction (ED) and diminished libido may be caused by testosterone imbalances. However, testosterone may be only one of several variables that contribute to ED.
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